Minimally invasive head and neck surgery has evolved to improve patients’ quality of life and to lessen the aftermath of the traditional radical surgery such as extensive tissue injury and organ loss. Integration of novel technologies and endoscopic surgery fundamental such as transoral laser microsurgery, transoral robotic surgery, and robotic thyroid surgery play roles in the minimally invasive head and neck surgery. There are evidence-based literatures of the minimally invasive head and neck surgery reporting the superior surgical outcomes and better quality of life for patients.