Objective: This paper studied the outcome of treatment in chronic suppurative otitis media comparing 8% Burow's solution and sofradex ear drops.
Material and Methods: A double-blind, randomized trial was conducted in 41 patients with chronic suppurative otitis media disease at Songklanagarind Hospital. The recorded is the basic characteristic data of all patients was recorded and the outcome of treatment in the two groups compared using Chi-square test ( p-value  <  0.05 ).
Results: Eighteen out of 25 patients were cured by using sofradex ear drops, and 7 of 16 were cured by using Burow’s solution. These results give a p = 0.103 which is not significant.
Conclusion: The result could not conclude which treatment is better. However, it is more likely to be the sofradex ear drop treatment group (72 : 43.75).