Ehrlichiosis is a zoonotic disease caused by intracellular bacteria. Disease transmission is via tick bite. There are two forms of human infection: human monocytic ehrlichiosis and human granulocytic ehrlichiosis. This infection has direct pathological effects on platelet and white blood cells, causing fever and anemia but no specific symptoms for the affected patients. However, there are some complications of this disease which can bring death. In this article, the authors review the literature on human ehrlichiosis infection.