Urinalysis can reveal diseases that have gone unnoticed because they do not produce striking signs or symptoms. The most cost-effective device used to screen urine is a paper or plastic dipstick with microchemical test pad. However, a careless doctor, nurse or assistant is entirely capable of misreading or misinterpreting the results. In this article, three case studies of the aberrant results from urine dipstick tests (urine pregnancy test, urine ketone test and urine drug screening) are presented and discussed. The first case is the case of urine pregnancy test with a lack of correspondence between the results of samples. The second case is that of drug interference effect on urine ketone test and the last is the case of urine amphetamine screening with discrepant results. The author also states the importance of quality management in all phases of urine strip testing.