Gross hematuria is the most common presentation in genitourinary cancer patients. Patient with radiation cystitis also have similar presentation. Radiation cystitis can cause hematuria in various degrees, most of patients usually had mild to moderate degree which can be successfully treated with conservative treatment. In some patients, degree of hematuria may be severe that leads to mortality, correct treatment may decrease mortality rate. We review the current literature regarding the current management of radiation cystitis.