Objective: To evaluate the perioperative outcomes of pancreaticoduodenectomy at Suratthani Hospital.

Material and Method: Retrospective study of data from 26 patients who underwent pancreaticoduodenectomy

from January 2012 through January 2015, at Suratthani Hospital. The primary endpoints are the morbidity and mortality rate.

Results: Twenty six patients (17 male and 9 female) with mean age 61.1±11.9 years were analyzed. The overall

hospital mortality rate was 11.5% (n=3). The morbidity rate was 61.5% (n=16). Delayed gastric emptying time (42.3%)

and pancreaticojejunal anastomotic leakage (30.8%) were the two most common complications. In this study,

preoperative and operative factors had no significant effect on morbidity rate.

Conclusion: Pancreaticoduodenectomy still has high morbidity and mortality rate. Further improvement of surgical

technique together with the good pre and postoperative care may help to reduce mortality and morbidity rate.