Objective: To study the mental health and associated factors of Prince of Songkla University

medical students.

Materials and methods: The study was a crosssectional survey study. The sample included all 1^st-6^th year medical students of the Faculty of Medicine, Prince of Songkla University. All medical students were invited to complete the questionnaire for demographic data, and the Thai General Health Questionnaire 12 (GHQ-12). Mean, percentage, Chi-square, rank sum test and logistic regression were used to analyze the data.

Results: There were 646 medical students (74.5%) who completed the questionnaire. 188 (29.1%) of

the medical students had a Thai GHQ-12 score more than 2 which indicate chance of mental health problem. Multivariate analysis revealed three factors significantly associated with the students’ mental health: gender, medical class, and domicile. Female medical students had a 1.73 times higher risk of mental health problems than males. The 2^nd year medical students were 3.56 times more likely to have mental health problems than 1^st year medical students. Medical students from rural areas were 2.01 times more likely to suffer mental health problems than the medical students from an urban area.

Conclusion: Three factors that were significantly associated with the risk of mental health problems in medical students were gender, medical class, and domicile.