Computed tomography colonography (CTC) is widely accepted as an effective new tool for screening and diagnosis of colorectal carcinoma. This procedure is noninvasive, requires no sedation, has a short examination time and the risk of colonic perforation is low. CTC has been used in many sites which have multidetector computed tomography (MDCT). This review summarizes the accuracy, CTC technique and bowel cleansing, CT protocol, indications, contraindications and complications of CTC.